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Article

Global variation in the frequencies of functionally different catechol-O-methyltransferase alleles.

Biological psychiatry - 15 Aug 1999

Palmatier M A, Kang A M, Kidd K K

Abstract excerpt

BACKGROUND: Catechol-O-methyltransferase (COMT) has been investigated as a candidate gene in many neurologic disorders involving catecholaminergic systems. The NlaIII restriction site polymorphism (RSP) at COMT is a G<-->A (site absent<-->site present) single nucleotide polymorphism (SNP) at nucleotide 322/472 (in the short or long mRNA) that results in a Val<-->Met polymorphism at amino acid 108/158 (in soluble...

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Source

Identifiers

PMID: 10459407
DOI: 10.1016/s0006-3223(99)00098-0

Genes

COMT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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