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Article

Loss of CD95 expression is linked to most but not all p53 mutants in European hepatocellular carcinoma.

Journal of molecular medicine (Berlin, Germany) - 1 Oct 2001

Volkmann M, Schiff J H, Hajjar Y, Otto G, Stilgenbauer F, Fiehn W, Galle P R, Hofmann W J

Abstract excerpt

Experimental data have shown p53-dependent CD95 induction to be associated with increased levels of apoptosis after cytostatic treatment in hepatoma cells. A study of Japanese hepatocellular carcinoma (HCC) has reported an inverse correlation between CD95 and p53 expression. To examine the interaction of p53 and CD95 in tumors we investigated which alterations in p53 can be linked to loss of CD95 expression in...

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Share to Carcinoma, Hepatocellular
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 11692157
DOI: 10.1007/s001090100244

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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