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Article

CD95 antigen mutations in hematopoietic malignancies.

Leukemia & lymphoma - 1 Jan 2000

Landowski T H, Moscinski L, Burke R, Buyuksal I, Painter J S, Goldstein S, Dalton W S

Abstract excerpt

The CD95 receptor, also known as Fas/Apo-1, is a member of the Tumor Necrosis Factor receptor (TNF-R) family of death receptors. Apoptosis mediated by CD95 plays a central role in maintaining homeostasis of the immune system. Dysregulation of the CD95 apoptotic pathway has been proposed as a mechanism of oncogenesis by providing a survival advantage to potentially malignant cells. This extended lifespan could...

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Identifiers

PMID: 11697638
DOI: 10.3109/10428190109097702

Genes

TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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