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Article

PTEN does not modulate GLUT4 translocation in rat adipose cells under physiological conditions.

Biochemical and biophysical research communications - 9 Nov 2001

Mosser V A, Li Y, Quon M J

Abstract excerpt

PTEN is a 3'-inositol lipid phosphatase that dephosphorylates products of PI 3-kinase. Since PI 3-kinase is required for many metabolic actions of insulin, we investigated the role of PTEN in insulin-stimulated translocation of GLUT4. In control rat adipose cells, we observed a approximately 2-fold increase in cell surface GLUT4 upon maximal insulin stimulation. Overexpression of wild-type PTEN abolished this...

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Share to 3T3 Cells
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Share to ets-Domain Protein Elk-1

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Glucose Transporter Type 4

Share to Mitogen-Activated Protein Kinase 1

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Source

Identifiers

PMID: 11689011
DOI: 10.1006/bbrc.2001.5876

Genes

PTEN
CBR3

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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