Article
Roles of 1-phosphatidylinositol 3-kinase and ras in regulating translocation of GLUT4 in transfected rat adipose cells.
Molecular and cellular biology - 1 Oct 1995
Quon M J, Chen H, Ing B L, Liu M L, Zarnowski M J, Yonezawa K, Kasuga M, Cushman S W, Taylor S I
Abstract excerpt
Insulin stimulates glucose transport in insulin target tissues by recruiting glucose transporters (primarily GLUT4) from an intracellular compartment to the cell surface. Previous studies have demonstrated that insulin receptor tyrosine kinase activity and subsequent phosphorylation of insulin re...
Topics
- Adipocytes
- Androstadienes
- Animals
- Biological Transport
- Cell Membrane
- Cells, Cultured
- Glucose Transporter Type 4
- Hemagglutinins
- Insulin
- Male
- Monosaccharide Transport Proteins
- Muscle Proteins
- Mutation
- Oncogene Protein p21(ras)