Article
Molecular regulation of GLUT-4 targeting in 3T3-L1 adipocytes.
The Journal of cell biology - 1 Sept 1995
Marsh B J, Alm R A, McIntosh S R, James D E
Abstract excerpt
Insulin stimulates glucose transport in muscle and adipose tissue by triggering the movement of the glucose transporter GLUT-4 from an intracellular compartment to the cell surface. Fundamental to this process is the intracellular sequestration of GLUT-4 in nonstimulated cells. Two distinct targeting motifs in the amino and carboxy termini of GLUT-4 have been previously identified by expressing chimeras comprised...
Topics
- 3T3 Cells
- Adipocytes
- Alanine
- Animals
- Epitopes
- Gene Expression
- Glucose Transporter Type 4
- Insulin
- Leucine
- Mice
- Monosaccharide Transport Proteins
- Muscle Proteins