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Article

Activity, phosphorylation state and subcellular distribution of GLUT4-targeted Akt2 in rat adipose cells.

Journal of cell science - 1 Sept 2003

Chen Xiaoli, Al-Hasani Hadi, Olausson Torbjorn, Wenthzel Ann-Marie, Smith Ulf, Cushman Samuel W

Abstract excerpt

In this study, fusion of the kinase domain of Akt2 to the cytosolic C terminus of exofacially-HA-tagged GLUT4 is used to investigate the activity, phosphorylation state and subcellular localization of Akt2 specifically targeted to the GLUT4-trafficking pathway in rat adipose cells. Fusion of wild-type (wt) Akt2, but not a kinase-dead (KD) mutant results in constitutive targeting of the HA-GLUT4 fusion protein to...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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PMID: 12876218
DOI: 10.1242/jcs.00675

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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