Article
Over-expression of DREF in the Drosophila wing imaginal disc induces apoptosis and a notching wing phenotype.
Genes to cells : devoted to molecular & cellular mechanisms - 1 Oct 2001
Yoshida H, Inoue Y H, Hirose F, Sakaguchi K, Matsukage A, Yamaguchi M
Abstract excerpt
BACKGROUND: DNA replication-related element binding factor (DREF) has been suggested to be involved in regulation of DNA replication- and proliferation-related genes in Drosophila. While the effects on the mutation in the DNA replication-related element (DRE) in cultured cells have been studied extensively, the consequences of elevating wild-type DREF activity in developing tissues have hitherto remained unclear....
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