Article
DRONC coordinates cell death and compensatory proliferation.
Molecular and cellular biology - 1 Oct 2006
Kondo Shu, Senoo-Matsuda Nanami, Hiromi Yasushi, Miura Masayuki
Abstract excerpt
Accidental cell death often leads to compensatory proliferation. In Drosophila imaginal discs, for example, gamma-irradiation induces extensive cell death, which is rapidly compensated by elevated proliferation. Excessive compensatory proliferation can be artificially induced by "undead cells" that are kept alive by inhibition of effector caspases in the presence of apoptotic stimuli. This suggests that...
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