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Drosophila DREF acting via the JNK pathway is required for thorax development.

Genesis (New York, N.Y. : 2000) - 1 Aug 2012

Yoshioka Yasuhide, Nguyen Trong Tue, Fujiwara Shunsuke, Matsuda Risa, Valadez-Graham Viviana, Zurita Mario, Yamaguchi Masamitsu

Abstract excerpt

The Drosophila Jun N-terminal kinase (JNK) gene basket (bsk) promoter contains a DNA replication-related element (DRE)-like sequence, raising the possibility of regulation by the DNA replication-related element-binding factor (DREF). Chromatin immunoprecipitation assays with anti-DREF IgG showed the bsk gene promoter region to be effectively amplified. Luciferase transient expression assays revealed the DRE-like...

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PMID: 22307950
DOI: 10.1002/dvg.22017

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