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Article

Drosophila distal-less negatively regulates dDREF by inhibiting its DNA binding activity.

Biochimica et biophysica acta - 1 Jul 2006

Hayashi Yuko, Kato Masaki, Seto Hirokazu, Yamaguchi Masamitsu

Abstract excerpt

The Drosophila DNA replication-related element binding factor (dDREF) is required for expression of many proliferation-related genes carrying the DRE sequence, 5'-TATCGATA. Over-expression of dDREF in the eye imaginal disc induces ectopic DNA synthesis, apoptosis and inhibition of photoreceptor cell specification, and results in rough eye phenotype in adults. In the present study, half dose reduction of the...

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PMID: 16949685
DOI: 10.1016/j.bbaexp.2006.07.002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Drosophila distal-less negatively regulates dDREF by inhibiting its DNA binding activity.PMID 16949685Read ↗

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