Article
Drosophila distal-less negatively regulates dDREF by inhibiting its DNA binding activity.
Biochimica et biophysica acta - 1 Jul 2006
Hayashi Yuko, Kato Masaki, Seto Hirokazu, Yamaguchi Masamitsu
Abstract excerpt
The Drosophila DNA replication-related element binding factor (dDREF) is required for expression of many proliferation-related genes carrying the DRE sequence, 5'-TATCGATA. Over-expression of dDREF in the eye imaginal disc induces ectopic DNA synthesis, apoptosis and inhibition of photoreceptor c...
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