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Article

Correlation between mutations in the interferon sensitivity-determining region of NS5A protein and viral load of hepatitis C virus subtypes 1b, 1c, and 2a.

Journal of clinical microbiology - 1 Nov 2001

Lusida M I, Nagano-Fujii M, Nidom C A, Soetjipto, Handajani R, Fujita T, Oka K, Hotta H

Abstract excerpt

In the present study, we analyzed the possible relationship between interferon (IFN) sensitivity-determining region (ISDR) sequence variation of various hepatitis C virus (HCV) subtypes and serum HCV titers in Indonesian patients without IFN treatment. The viremia titers (mean +/- standard deviation) of HCV subtype 1b (HCV-1b) isolates with low (three or fewer) and high (four or more) numbers of ISDR mutations...

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Source

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Identifiers

PMID: 11682498
DOI: 10.1128/JCM.39.11.3858-3864.2001
PMCID: PMC88455

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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