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Article

Mutations in interferon sensitivity-determining region of hepatitis C virus: its relation to change in viral load.

The American journal of gastroenterology - 1 Jul 2000

Terazawa Y, Yoshioka K, Kobayashi M, Watanabe K, Ishigami M, Yano M, Takagi K, Kakumu S

Abstract excerpt

OBJECTIVE: Interferon sensitivity-determining region (ISDR) in nonstructural region 5A of hepatitis C virus (HCV) genotype-1b has been reported to be associated with viral load. Viral load is usually small in the patients with mutant type (four or more amino acid substitutions, compared with HCV-...

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Identifiers

PMID: 10925985
DOI: 10.1111/j.1572-0241.2000.02176.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-10925985-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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