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Article

Amino acid substitutions in the nonstructural region 5A of hepatitis C virus genotypes 2a and 2b and its relation to viral load and response to interferon.

The American journal of gastroenterology - 1 Apr 2002

Kobayashi Makoto, Watanabe Kazumasa, Ishigami Masatoshi, Murase Kenichi, Ito Hiroshi, Ukai Koji, Yano Motoyoshi, Takagi Kenji, Hattori Masaki, Kakumu Shinichi, Yoshioka Kentaro

Abstract excerpt

OBJECTIVES: The interferon sensitivity-determining region (ISDR) in nonstructural region 5A (NS5A) of hepatitis C virus genotype 1b has been reported to correlate with response to interferon therapy and viral load. Recently the correlation between NS5A and response to interferon in genotype 2a was also reported. We examined the region of genotypes 2a and 2b corresponding to the ISDR of genotype lb to elucidate...

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Identifiers

PMID: 12003437
DOI: 10.1111/j.1572-0241.2002.05619.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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