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Article

Mutations in the nonstructural region 5B of hepatitis C virus genotype 1b: their relation to viral load, response to interferon, and the nonstructural region 5A.

Journal of medical virology - 1 Apr 2005

Watanabe Kazumasa, Yoshioka Kentaro, Yano Motoyoshi, Ishigami Masatoshi, Ukai Koji, Ito Hiroshi, Miyata Fumiyuki, Mizutani Tetsuya, Goto Hidemi

Abstract excerpt

The nonstructural 5B (NS5B) protein of hepatitis C virus possesses RNA-dependent RNA polymerase activity and plays an essential role in viral replication. The mutations in NS5B were determined and the correlation with viral load and response to interferon (IFN) were assessed. The entire NS5B regi...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15714488
DOI: 10.1002/jmv.20301

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15714488-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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