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Article

Mutations in ISDR of NS5A gene influence interferon efficacy in Chinese patients with chronic hepatitis C virus genotype 1b infection.

Journal of gastroenterology and hepatology - 1 Nov 2007

Shen Chuanlai, Hu Ting, Shen Ling, Gao Lei, Xie Wei, Zhang Jianqiong

Abstract excerpt

BACKGROUND AND AIM: The interferon sensitivity determining region (ISDR) in the non-structural 5A protein (NS5A) gene of hepatitis C virus genotype 1b (HCV-1b) has been demonstrated in Japanese patients; however, contradictory data have been reported from other parts of the world, particularly from Europe and the USA. This study investigated whether mutations in the ISDR of NS5A gene influence interferon efficacy...

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Source

Identifiers

PMID: 17914967
DOI: 10.1111/j.1440-1746.2006.04566.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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