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Article

The distribution of UV photoproducts along the human p53 gene and its relation to mutations in skin cancer.

Oncogene - 1 Aug 1993

Tornaletti S, Rozek D, Pfeifer G P

Abstract excerpt

Mutations in the p53 gene have been found in a large proportion of human skin cancers. These mutations show the same characteristics as mutations induced by UV light in experimental systems. To establish correlations between formation of DNA adducts by a known carcinogen and incidence of mutations within a specific human gene, we have investigated the formation of UV-induced photoproducts along exons 5-9 of the...

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PMID: 8336934

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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