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Article

p53 mutations implicate sunlight in post-transplant skin cancer irrespective of human papillomavirus status.

Oncogene - 2 Oct 1997

McGregor J M, Berkhout R J, Rozycka M, ter Schegget J, Bouwes Bavinck J N, Brooks L, Crook T

Abstract excerpt

Mutations in p53 were detected in 11/23 (48%) of non melanoma skin cancers in renal allograft recipients and in 5/8 (63%) of sporadic tumours from immune competent patients. 9/12 (75%) of mutations in transplant patients and all 5 mutations in non transplant tumours were consistent with damage caused by ultraviolet (u.v.) irradiation. DNA sequences, predominantly of the epidermodysplasia verruciformis (EV)...

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Source

Identifiers

PMID: 9349508
DOI: 10.1038/sj.onc.1201339

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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p53 mutations implicate sunlight in post-transplant skin cancer irrespective of human papillomavirus status.PMID 9349508Read ↗

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