Carcinogen-specific mutational pattern in the p53 gene in ultraviolet B radiation-induced squamous cell carcinomas of mouse skin.

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Article

Carcinogen-specific mutational pattern in the p53 gene in ultraviolet B radiation-induced squamous cell carcinomas of mouse skin.

Cancer research - 15 Nov 1992

Kress S, Sutter C, Strickland P T, Mukhtar H, Schweizer J, Schwarz M

Abstract excerpt

We have examined 35 epidermal tumors induced in mice of four different strains by chronic exposure to ultraviolet B radiation for the presence of aberrations in the p53 tumor suppressor gene. Polymerase chain reaction products from p53 exons 5 to 8 were screened by single-strand conformation poly...

Topics

Animals
Base Sequence
Carcinoma, Squamous Cell
Codon
DNA, Neoplasm
Exons
Genes, p53
Humans
Mice
Mice, Inbred BALB C
Mice, Inbred C3H
Molecular Sequence Data
Mutation
Neoplasms, Radiation-Induced
Polymerase Chain Reaction
Skin Neoplasms
Ultraviolet Rays

Source

Open in PubMed

Identifiers

PMID: 1423288

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1423288-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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