Article
Vps26p, a component of retromer, directs the interactions of Vps35p in endosome-to-Golgi retrieval.
Molecular biology of the cell - 1 Oct 2001
Reddy J V, Seaman M N
Abstract excerpt
Endosome-to-Golgi retrieval of the carboxypeptidase Y receptor Vps10p is mediated by a recently discovered membrane coat complex termed retromer. Retromer comprises five conserved proteins: Vps35p, Vps29p, Vps5p, Vps17p, and Vps26p. Vps35p recognizes cargo molecules such as Vps10p and interacts strongly with Vps29p. Vps5p forms a subcomplex with Vps17p and has been proposed to play a structural role by...
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