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Article

Retromer's Role in Endosomal Trafficking and Impaired Function in Neurodegenerative Diseases.

Current protein & peptide science - 1 Jan 2017

Follett Jordan, Bugarcic Andrea, Collins Brett M, Teasdale Rohan D

Abstract excerpt

The retromer complex is a highly conserved membrane trafficking assembly composed of three proteins - Vps26, Vps29 and Vps35 - that were identified over a decade ago in Saccharomyces cerevisiae (S. cerevisiae). Initially, mammalian retromer was shown to sort transmembrane proteins from the endosome to the trans-Golgi network (TGN), though recent work has identified a critical role for retromer in multiple...

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Identifiers

PMID: 26965691
DOI: 10.2174/1389203717666160311121246

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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