Article
Effect of ApoE and tau on age of onset of progressive supranuclear palsy and multiple system atrophy.
Neuroscience letters - 19 Oct 2001
Morris H R, Schrag A, Nath U, Burn D, Quinn N P, Daniel S, Wood N W, Lees A J
Abstract excerpt
In addition to allelic association between genetic polymorphisms and diseases, modulation of age of onset is a well recognised effect of disease susceptibility genes. The ApoE epsilon4 allele is associated with an earlier age of onset of sporadic and familial Alzheimer's disease. It has been suggested that the tau genotype influences the age of onset of progressive supranuclear palsy (PSP), a form of atypical...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.