Article
Effect of MAPT and APOE on prognosis of progressive supranuclear palsy.
Neuroscience letters - 11 Sept 2006
Baba Yasuhiko, Putzke John D, Tsuboi Yoshio, Josephs Keith A, Thomas Natalie, Wszolek Zbigniew K, Dickson Dennis W
Abstract excerpt
To assess genetic influence on the clinical presentation of progressive supranuclear palsy (PSP), the genetic effect on disease course was examined for variants in the tau gene (MAPT) and the gene for apolipoprotein E (APOE) in 58 cases of pathologically confirmed PSP. Clinical indicators of disease course included age at symptomatic onset (AAO), age at death (AAD), and disease duration (DD) and the genetic...
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