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Article

Apolipoprotein E and presenilin-1 genotypes in Huntington's disease.

Journal of neurology - 1 Jul 1999

Panas M, Avramopoulos D, Karadima G, Petersen M B, Vassilopoulos D

Abstract excerpt

Huntington's disease (HD) is an autosomal dominant degenerative disease of the central nervous system manifested by involuntary movements (chorea), psychiatric manifestations, and cognitive impairment with a variable age at onset. This variability is mainly attributed to genetic factors. The so-called aging genes [e.g., those for apolipoprotein E (APOE) and presenilin-1 (PS-1) have been implicated in determining...

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Source

Identifiers

PMID: 10463359
DOI: 10.1007/s004150050406

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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