Article
Relationship of apolipoprotein E and age at onset to Parkinson disease neuropathology.
Journal of neuropathology and experimental neurology - 1 Feb 2006
Ghebremedhin Estifanos, Del Tredici Kelly, Vuksic Mario, Rüb Udo, Thal Dietmar R, Burbach Guido J, Rosenberger Albert, Bickeböller Heike, Deller Thomas, de Vos Rob A I, Jansen Steur Ernst N H, Braak Heiko
Abstract excerpt
Previous studies investigating the association between apolipoprotein E (APOE) genotypes and Parkinson disease (PD) have yielded conflicting results, and only a few have addressed APOE as a possible determinant of PD pathology. Therefore, we aimed to evaluate the relationship between APOE and PD as well as APOE and PD pathology. We studied 108 pathologically verified patients with PD and 108 controls pair-matched...
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