Article
A new locus for coeliac disease mapped to chromosome 15 in a population isolate.
Human genetics - 1 Jul 2002
Woolley Niina, Holopainen Päivi, Ollikainen Vesa, Mustalahti Kirsi, Mäki Markku, Kere Juha, Partanen Jukka
Abstract excerpt
Coeliac disease is a common multifactorial disease with a strong genetic component, which is not entirely explained by the HLA association. Four previous whole-genome screens have produced somewhat inconsistent results suggesting genetic heterogeneity. We attempted to overcome this problem by performing a genome-wide scan in a Finnish sub-population, expected to be more homogeneous than the general population of...
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