Article
Saturation of the 5q31-q33 candidate region for coeliac disease.
Annals of human genetics - 1 May 2003
Percopo S, Babron M-C, Whalen M, De Virgiliis S, Coto I, Clerget-Darpoux F, Landolfo F, Greco L
Abstract excerpt
The first genome wide screening performed on Italian affected sib-pair families (Greco et al. 1998) gave evidence for linkage with coeliac disease in the 5q region. This finding was replicated in a second independent dataset (Greco et al. 2001). Overall, pooling both samples, the highest MLS value (2.92) was found for the most centromeric marker tested, D5S640. In the present study, the 5q31-q33 region was...
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