Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetics in coeliac disease.

Best practice & research. Clinical gastroenterology - 1 Jun 2005

van Heel David A, Hunt Karen, Greco Luigi, Wijmenga Cisca

Abstract excerpt

Coeliac disease has a strong genetic component, higher than for many other common complex diseases. Possession of the HLA-DQ2 variant is required for presentation of disease causing dietary antigens to T cells, although this is also common in the healthy population. Non-HLA genetic factors account for the majority of heritable risk. Linkage studies have identified promising regions on chromosomes 5 and 19, with...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Celiac Disease
Share to Celiac Disease Research and Management
Share to Clinical Trials as Topic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Diabetes and associated disorders

Share to Galectins and Cancer Biology

Share to CTLA4 gene

Share to ICOS gene

Share to Genetic Predisposition to Disease

Source

Identifiers

PMID: 15925839
DOI: 10.1016/j.bpg.2005.01.001

Genes

CTLA4
ICOS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetics in coeliac disease.PMID 15925839Read ↗

HLA in coeliac disease: Unravelling the complex genetics of a complex disorderSemantic proximity Read ↗

A genetic perspective on coeliac disease.Semantic proximity Read ↗

Genetics of coeliac diseaseSemantic proximity Read ↗

Genetics and pathogenesis of coeliac disease.Semantic proximity Read ↗

Shared genetics in coeliac disease and other immune-mediated diseases.Semantic proximity Read ↗

The genetics of celiac disease: A comprehensive review of clinical implications.Semantic proximity Read ↗

A combined genetics and genomics approach to unravelling molecular pathways in coeliac disease.Semantic proximity Read ↗

Celiac disease genetics: past, present and future challenges.Semantic proximity Read ↗

From genome-wide association studies to disease mechanisms: celiac disease as a model for autoimmune diseases.Semantic proximity Read ↗

Searching for genes influencing a complex disease: the case of coeliac disease.Semantic proximity Read ↗

Phenome-wide association study in adult coeliac disease: role of HLA subtype.Semantic proximity Read ↗

A common CTLA4 haplotype associated with coeliac disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.