Article
Variants within protectin (CD59) and CD44 genes linked to an inherited haplotype in a family with coeliac disease.
Tissue antigens - 1 Mar 2009
Vidal C, Borg J, Xuereb-Anastasi A, Scerri C A
Abstract excerpt
Coeliac disease (CD) is an autoimmune disorder characterised by inflammation, villous atrophy and hyperplasia of the small intestinal mucosa that affects genetically susceptible individuals. A genome-wide scan was performed in 17 family members with high incidence of CD. Highest nonparametric linkage (NPL) and logarithm of odds (LOD) scores were of 6.21 (P = 0.0107) and 2.57, respectively, to a region on...
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