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Article

The Lurcher mutation reveals Ca(2+) permeability and PKC modification of the GluRdelta channels.

Neuroscience research - 1 Oct 2001

Ikeno K, Yamakura T, Yamazaki M, Sakimura K

Abstract excerpt

The physiological function of the GluRdelta subfamily which is one of the glutamate receptor (GluR) channel subunits has not yet been clarified, because no GluR channel activity has been detected in heterologous expression systems. The Lurcher mutation, a point mutation of the GluRdelta2 subunit, converts it into a constitutively active and cation-permeating channel. We introduced this mutation into GluRdelta1...

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PMID: 11591446
DOI: 10.1016/s0168-0102(01)00277-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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