Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Properties of single two-pore domain TREK-2 channels expressed in mammalian cells.

The Journal of physiology - 15 Aug 2007

Kang Dawon, Choe Changyong, Cavanaugh Eric, Kim Donghee

Abstract excerpt

TREK-2 (K2P10.1), a member of the two-pore domain K+ (K2P) channel family, provides the background K+ conductance in many cell types, and is a target of neurotransmitters that act on receptors coupled to Gs and Gq. We report here that TREK-2 exhibits small (TREK-2S) and large (TREK-2L) conductanc...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chlorocebus aethiops
Share to COS Cells
Share to Electrophysiology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Oocytes

Share to Patch-Clamp Techniques

Share to Potassium Channels, Calcium-Activated

Share to Potassium Channels, Tandem Pore Domain

Share to Xenopus laevis

Source

Open in PubMed Open full text

Identifiers

PMID: 17540699
DOI: 10.1113/jphysiol.2007.136150
PMCID: PMC2277227

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17540699-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Properties of single two-pore domain TREK-2 channels expressed in mammalian cells.PMID 17540699Read ↗

Functional Expression of TRESK-2, a New Member of the Tandem-pore K+ Channel FamilySemantic proximity Read ↗

Control of the single channel conductance of K2P10.1 (TREK-2) by the amino-terminus: role of alternative translation initiation.Semantic proximity Read ↗

Expression pattern and functional characteristics of two novel splice variants of the two-pore-domain potassium channel TREK-2.Semantic proximity Read ↗

Mechanism of inhibition of TREK-2 (K2P10.1) by the Gq-coupled M3 muscarinic receptor.Semantic proximity Read ↗

Sequential phosphorylation mediates receptor- and kinase-induced inhibition of TREK-1 background potassium channels.Semantic proximity Read ↗

Dominant negative effects of a non-conducting TREK1 splice variant expressed in brain.Semantic proximity Read ↗

Selective Small Molecule Activators of TREK-2 Channels Stimulate Dorsal Root Ganglion c-Fiber Nociceptor Two-Pore-Domain Potassium Channel Currents and Limit Calcium Influx.Semantic proximity Read ↗

Identification and characterization of alternative splice variants of the mouse Trek2/Kcnk10 gene.Semantic proximity Read ↗

Critical contribution of the intracellular C-terminal region to TRESK channel activity is revealed by the epithelial Na+ current ratio method.Semantic proximity Read ↗

Extracellular acidification exerts opposite actions on TREK1 and TREK2 potassium channels via a single conserved histidine residue.Semantic proximity Read ↗

Mtap2 is a constituent of the protein network that regulates twik-related K+ channel expression and trafficking.Semantic proximity Read ↗

Na(+)-induced inward rectification in the two-pore domain K(+) channel, TASK-2.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.