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Article

Functional Roles of the Edited Isoform of GluA2 in GluA2-Containing AMPA Receptor Channels.

Biochemistry - 21 Mar 2017

Han Yan, Lin Chi-Yen, Niu Li

Abstract excerpt

GluA2R is the edited isoform at the Q/R site of the AMPA receptor GluA2 subunit. In vivo, GluA2R assembles with other AMPA receptor subunits into a high-conductance, tetrameric complex. Here we study the functional role of GluA2R in the context of GluA1/2R and GluA2Q/2R heteromeric receptors, using whole-cell recording and a laser-pulse photolysis technique. We find the incorporation of GluA2R with GluA1 or...

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PMID: 28244309
DOI: 10.1021/acs.biochem.6b01041

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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