Article
Ca2+ permeability of unedited and edited versions of the kainate selective glutamate receptor GluR6.
Proceedings of the National Academy of Sciences of the United States of America - 15 Jan 1993
Egebjerg J, Heinemann S F
Abstract excerpt
The Ca2+ permeability of the kainate selective glutamate receptor GluR6 depends on the editing of the RNA (or DNA). The unedited version of GluR6, GluR6Q, encodes a glutamine at position 621 (Q/R site) and exhibits a Ca2+/monovalent ion permeability ratio of 1.2, while the edited version of GluR6...
Topics
- Amino Acid Sequence
- Animals
- Calcium
- Cations
- Cell Membrane Permeability
- Electric Conductivity
- Genetic Variation
- Ion Channels
- Membrane Potentials
- Molecular Sequence Data
- Oocytes
- RNA Editing
- Receptors, Glutamate
- Receptors, Kainic Acid
- Xenopus