Article
A tournament of linkage tests in complex inheritance.
Human heredity - 1 Jan 2001
Zhang W, Tapper W, Collins A, Jacobs K B, Elston R C, Morton N E
Abstract excerpt
The performance of some weakly parametric linkage tests in common use was compared on 200 replicates of oligogenic inheritance from Genetic Analysis Workshop 10. Each random sample for the quantitative trait was dichotomized at different thresholds and also selected through 2 affected sibs, generating 8 combinations of sample and variable. The variance component program SOLAR performed best with a continuous...
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