Article
Combining information within and between pedigrees for mapping complex traits.
American journal of human genetics - 1 Apr 1997
Teng J, Siegmund D
Abstract excerpt
This paper is concerned with efficient strategies for gene mapping using pedigrees containing small numbers of affecteds and identity-by-descent data from closely spaced markers throughout the genome. Particular attention is paid to additive traits involving phenocopies and/or locus heterogeneity...
Topics
- Chromosome Mapping
- Genotype
- Humans
- Likelihood Functions
- Models, Genetic
- Nuclear Family
- Pedigree
- Phenotype