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Article

Linkage and association analysis in pedigrees from different populations.

BMC genetics - 30 Dec 2005

Beyene Joseph, Yan Jun, Greenwood Celia M T

Abstract excerpt

Using the Genetic Analysis Workshop 14 simulated datasets we carried out nonparametric linkage analyses and applied a log-linear method for analysis of case-parent-triad data with stratification on parental mating type. We proposed and applied a random effect modelling approach to explore the impact of population heterogeneity on tests of association between genetic markers and disease status. The estimated...

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Identifiers

PMID: 16451671
DOI: 10.1186/1471-2156-6-S1-S59
PMCID: PMC1866724

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