Article
Association analysis of a functional G protein beta3 subunit gene polymorphism (C825T) in mood disorders.
Neuropsychobiology - 1 Jan 2001
Lin C N, Tsai S J, Hong C J
Abstract excerpt
The guanine nucleotide-binding proteins (G proteins), heterotrimers consisting of alpha, beta and gamma subunits, convey signals initiated by the activation of many neurotransmitter receptors. Evidence for involvement of the G proteins in mood disorders relies on the effects of mood stabilizers and antidepressants on G protein function. In addition, abnormalities in the expression of G proteins have been...
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