Article
C825T polymorphism in the G protein beta3-subunit gene is associated with seasonal affective disorder.
Biological psychiatry - 1 Oct 2003
Willeit Matthäus, Praschak-Rieder Nicole, Zill Peter, Neumeister Alexander, Ackenheil Manfred, Kasper Siegfried, Bondy Brigitta
Abstract excerpt
BACKGROUND: Heterotrimeric G proteins play a pivotal role in the intracellular transduction of many transmitter-receptor interactions. Alterations in signal transduction and in G protein concentrations have been reported in seasonal and nonseasonal affective disorder. A single-nucleotide polymorp...
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