Article
The C825T Polymorphism of the G-Protein β3 Gene as a Risk Factor for Depression: A Meta-Analysis.
PloS one - 1 Jan 2015
Fang Liang, Zhou Chanjuan, Bai Shunjie, Huang Chenglong, Pan Junxi, Wang Ling, Wang Xinfa, Mao Qiang, Sun Lu, Xie Peng
Abstract excerpt
BACKGROUND: TheG-protein β3 gene (GNβ3) has been implicated in psychiatric illness through its effects upon intracellular transduction of several neurotransmitter receptors. Multiple studies have investigated the relationship of the C825T polymorphism of the GNβ3 gene (GNβ3 C825T) to depression and antidepressant response. However, the relationship between GNβ3 C825T and depression remains inconsistent....
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