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Article

SSRIs antidepressant activity is influenced by G beta 3 variants.

European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology - 1 Mar 2003

Serretti Alessandro, Lorenzi Cristina, Cusin Cristina, Zanardi Raffaella, Lattuada Enrico, Rossini David, Lilli Roberta, Pirovano Adele, Catalano Marco, Smeraldi Enrico

Abstract excerpt

The aim of the present study was to test a possible effect of the G-protein beta3-subunit (Gbeta3) C825T gene variant on the antidepressant activity of selective serotonin reuptake inhibitors (SSRIs) in a sample of major and bipolar depressives, with or without psychotic features. Four hundred and ninety inpatients were treated with fluvoxamine 300 mg/day (n=362) or paroxetine 40 mg/day (n=128) and either placebo...

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Identifiers

PMID: 12650956
DOI: 10.1016/s0924-977x(02)00154-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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