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Article

Tubular phenotypic change in progressive tubulointerstitial fibrosis in human glomerulonephritis.

American journal of kidney diseases : the official journal of the National Kidney Foundation - 1 Oct 2001

Jinde K, Nikolic-Paterson D J, Huang X R, Sakai H, Kurokawa K, Atkins R C, Lan H Y

Abstract excerpt

There is much debate over the origins of fibroblast-type cells that accumulate in interstitial fibrosis. A controversial hypothesis, supported by data from animal and cell-culture studies, is that fibroblast-type cells can derive from tubular epithelial cells by a process of epithelial-mesenchymal transdifferentiation. However, to date, no evidence supports this postulate in human glomerulonephritis. This study...

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Source

Identifiers

PMID: 11576879
DOI: 10.1053/ajkd.2001.27693

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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