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Epithelial-mesenchymal transition in renal fibrosis - evidence for and against

6 May 2011

Abstract excerpt

Epithelial to mesenchymal transition (EMT) is a well established biological process in metazoan embryological development. Over the past 15 years, investigators have sought to establish whether EMT also occurs in renal epithelial cells, following kidney injury, and to show that the mesenchymal cells formed could give rise to myofibroblasts which populate the renal interstitium, causing fibrosis within it. There...

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PMID: 21554437
DOI: 10.1111/j.1365-2613.2011.00775.x

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