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Article

Mesangial phenotypic changes associated with cellular lesions in primary focal segmental glomerulosclerosis.

American journal of kidney diseases : the official journal of the National Kidney Foundation - 1 Nov 1997

Hattori M, Horita S, Yoshioka T, Yamaguchi Y, Kawaguchi H, Ito K

Abstract excerpt

Injury to glomerular visceral epithelial cells has been proposed as the initial step in glomerular scar formation in primary focal segmental glomerulosclerosis (FSGS); however, the subsequent process that ultimately results in glomerular scar formation remains uncertain. This study examined whether phenotypically altered mesangial cells determine the early progression of primary FSGS. Cellular lesion...

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PMID: 9370177
DOI: 10.1016/s0272-6386(97)90486-8

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