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Article

Phenotypic change of glomerular podocytes in primary focal segmental glomerulosclerosis: developmental paradigm?

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association - 1 Jan 2002

Ohtaka Akihiko, Ootaka Tetsuya, Sato Hiroshi, Ito Sadayoshi

Abstract excerpt

WT1 and Pax2 are transcription factors involved in kidney development and phenotypic regulation of glomerular epithelial cells. In primary focal segmental glomerulosclerosis (FSGS), the alteration of the podocyte is important for the development of the cellular lesion (CL) and glomerular scar formation. To investigate the contribution of WT1 and Pax2 to the development of the CL in primary FSGS,...

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Identifiers

PMID: 12386275
DOI: 10.1093/ndt/17.suppl_9.11

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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