Article
Genetic susceptibility of catechol-O-methyltransferase polymorphism in Japanese patients with breast cancer.
Oncology reports - 1 Sept 2005
Inoue Hiroshi, Shibuta Kenji, Matsuyama Ayumi, Yoshinaga Keishi, Sadanaga Noriaki, Ueo Hiroaki, Barnard Graham F, Mori Masaki
Abstract excerpt
Polymorphic catechol-O-methyltransferase (COMT) catalyzes the O-methylation of catechol estrogens. It has been reported that COMT polymorphism is a representative genetic trait related to the susceptibility of an individual to breast cancer. However, there is no consensus concerning the association between breast cancer in Japanese patients and COMT polymorphism. To analyze the polymorphism distribution in...
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