Article
Lack of association between catechol-O-methyltransferase Val108/158Met polymorphism and breast cancer risk: a meta-analysis of 25,627 cases and 34,222 controls.
Breast cancer research and treatment - 1 Jun 2010
Mao Chen, Wang Xi-Wen, Qiu Li-Xin, Liao Ru-Yan, Ding Hong, Chen Qing
Abstract excerpt
Epidemiological studies have evaluated the association between catechol-O-methyltransferase (COMT) Val108/158Met polymorphism and breast cancer risk. However, the results remain conflicting rather than conclusive. In order to derive a more precise estimation of the relationship, we performed this meta-analysis. Systematic searches of the PubMed and Medline databases were performed. A total of 41 studies including...
Topics
- Asian People
- Breast Neoplasms
- Case-Control Studies
- Catechol O-Methyltransferase
- Female
- Genetic Predisposition to Disease
- Humans
- Polymorphism, Genetic
- White People