Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Polymorphic catechol-O-methyltransferase gene, duration of estrogen exposure, and breast cancer risk: a nested case-control study in Taiwan.

Cancer detection and prevention - 1 Jan 2005

Lin Wei-Yu, Chou Yu-Ching, Wu Mei-Hsuan, Jeng Yi-Lin, Huang Han-Bin, You San-Lin, Chu Tang-Yuan, Chen Chien-Jen, Sun Chien-An

Abstract excerpt

BACKGROUND: Polymorphic catechol-O-methyltransferase (COMT) catalyzes the O-methylation of catechol estrogens, which are hypothesized to participate in estrogen-induced carcinogenesis. METHODS: We examined 87 cases and 341 population controls in Taiwan to determine the association between the functional genetic Val158Met polymorphism in membrane-bound form of COMT gene and female breast cancer risk. Odds ratios...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Breast Neoplasms
Share to Case-Control Studies

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Catechol O-Methyltransferase

Share to Environmental Exposure

Share to Estrogens

Share to Odds Ratio

Share to Polymorphism, Genetic

Share to Taiwan

Source

Identifiers

PMID: 16191465
DOI: 10.1016/j.cdp.2005.07.003

Genes

COMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Polymorphic catechol-O-methyltransferase gene, duration of estrogen exposure, and breast cancer risk: a nested case-control study in Taiwan.PMID 16191465Read ↗

Relationship between the Val158Met polymorphism of catechol O-methyl transferase and breast cancer.Semantic proximity Read ↗

Catechol-O-methyltransferase Val 108/158 Met polymorphism in premenopausal breast cancer patients.Semantic proximity Read ↗

Polymorphic catechol-O-methyltransferase gene, soy isoflavone intake and breast cancer in postmenopausal women: a case-control study.Semantic proximity Read ↗

Impact of Catechol-O-Methyltransferase Val 158Met (rs4680) Polymorphism on Breast Cancer Susceptibility in Asian PopulationSemantic proximity Read ↗

An association between the allele coding for a low activity variant of catechol-O-methyltransferase and the risk for breast cancer.Semantic proximity Read ↗

Catechol-O-methyltransferase Gene Polymorphism (Val158Met) and Development of Pre-eclampsia.Semantic proximity Read ↗

Lack of association between catechol-O-methyltransferase Val108/158Met polymorphism and breast cancer risk: a meta-analysis of 25,627 cases and 34,222 controls.Semantic proximity Read ↗

Association of COMT Val158Met polymorphism and breast cancer risk: an updated meta-analysis.Semantic proximity Read ↗

Contribution of catechol-O-methyltransferase Val158Met polymorphism to endometrial cancer risk in postmenopausal women: a meta-analysis.Semantic proximity Read ↗

Polymorphic catechol-O-methyltransferase gene and breast cancer risk.Semantic proximity Read ↗

Breast cancer risk associated with genotype polymorphism of the estrogen-metabolizing genes CYP17, CYP1A1, and COMT: a multigenic study on cancer susceptibility.Semantic proximity Read ↗

Catechol-O-methyltransferase Val 108/158 Met polymorphism and breast cancer risk: a case control study in Syria.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.