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Article

Catechol-O-methyltransferase Val 108/158 Met polymorphism in premenopausal breast cancer patients.

Toxicology - 15 Nov 2004

Sazci Ali, Ergul Emel, Utkan Nihat Zafer, Canturk Nuh Zafer, Kaya Guner

Abstract excerpt

There is compelling evidence to suggest that catecholestrogens may play a role in the development of breast cancer. Particularly, inactivation of catecholestrogens may prevent the genesis and arrest the development of breast cancer. Catechol-O-methyltransferase (COMT) is polymorphic and responsible for the detoxification of catecholestrogens. In the present study, we examined what role COMT gene polymorphisms may...

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Identifiers

PMID: 15388245
DOI: 10.1016/j.tox.2004.06.026

Genes

COMT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Catechol-O-methyltransferase Val 108/158 Met polymorphism in premenopausal breast cancer patients.PMID 15388245Read ↗

Relationship between the Val158Met polymorphism of catechol O-methyl transferase and breast cancer.Semantic proximity Read ↗

Lack of association between catechol-O-methyltransferase Val108/158Met polymorphism and breast cancer risk: a meta-analysis of 25,627 cases and 34,222 controls.Semantic proximity Read ↗

Catechol-O-methyltransferase Val158Met polymorphism and breast cancer risk in Asian population.Semantic proximity Read ↗

Association of COMT Val158Met polymorphism and breast cancer risk: an updated meta-analysis.Semantic proximity Read ↗

Polymorphic catechol-O-methyltransferase gene, soy isoflavone intake and breast cancer in postmenopausal women: a case-control study.Semantic proximity Read ↗

An association between the allele coding for a low activity variant of catechol-O-methyltransferase and the risk for breast cancer.Semantic proximity Read ↗

Catechol-O-methyltransferase Val 108/158 Met polymorphism and breast cancer risk: a case control study in Syria.Semantic proximity Read ↗

Polymorphic catechol-O-methyltransferase gene, duration of estrogen exposure, and breast cancer risk: a nested case-control study in Taiwan.Semantic proximity Read ↗

COMT Val158Met polymorphism and breast cancer risk: evidence from 26 case-control studies.Semantic proximity Read ↗

Impact of Catechol-O-Methyltransferase Val 158Met (rs4680) Polymorphism on Breast Cancer Susceptibility in Asian PopulationSemantic proximity Read ↗

Genetic susceptibility of catechol-O-methyltransferase polymorphism in Japanese patients with breast cancer.Semantic proximity Read ↗

Polymorphic catechol-O-methyltransferase gene and breast cancer risk.Semantic proximity Read ↗

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