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Article

Polymorphic catechol-O-methyltransferase gene and breast cancer risk.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Jun 2001

Mitrunen K, Jourenkova N, Kataja V, Eskelinen M, Kosma V M, Benhamou S, Kang D, Vainio H, Uusitupa M, Hirvonen A

Abstract excerpt

We examined 483 Finnish breast cancer cases and 482 population controls to determine the potential effect of catechol-O-methyltransferase (COMT) genotype in individual susceptibility to breast cancer. Odds ratios (ORs) and 95% confidence intervals (CIs) were estimated by unconditional logistic regression after adjustment for known or suspected risk factors for breast cancer. When studied separately by menopausal...

Topics

Aged
Aged, 80 and over
Breast Neoplasms
Case-Control Studies
Catechol O-Methyltransferase
Female
Genetic Predisposition to Disease
Genotype
Humans
Middle Aged

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Odds Ratio

Polymorphism, Genetic

Risk Factors

Source

Identifiers

PMID: 11401913

Genes

COMT

Provenance

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