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Article

A possible role of hypervariable region 1 quasispecies in escape of hepatitis C virus particles from neutralization.

Journal of viral hepatitis - 1 Sept 2001

Korenaga M, Hino K, Katoh Y, Yamaguchi Y, Okuda M, Yoshioka K, Okita K

Abstract excerpt

We examined serial changes in the hypervariable region 1(HVR1) quasispecies both in immune and nonimmune complexed hepatitis C virus (HCV) particles from 12 patients with chronic hepatitis C to elucidate the mechanism by which genetic diversification of HCV during the course of infection allows escape of virus from the humoural immune response. Immune and nonimmune complexes were separated by differential...

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Source

Identifiers

PMID: 11555190
DOI: 10.1046/j.1365-2893.2001.00305.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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